MCQ – 89111

Question

Cytogenetic studies in a 40-year-old woman with follicular lymphoma demonstrate a t(14;18) chromosomal translocation involving the bcl-2 gene. Constitutive expression of the protein encoded by the bcl-2 gene inhibits which of the following processes in this patient’s transformed lymphocytes?

A.

Apoptosis

B. DNA excision repair

C.

G1-to-S cell cycle progression

D.

Oxidative phosphorylation

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