Question
A 45-year-old female presents for routine follow-up for osteoarthritis. For her joint complaints, she has been taking celecoxib 100 mg twice daily for 9 months. Laboratory investigation reveals a creatinine of 2.5 with a prior baseline of 1.0, normal complements, and a urinalysis with +1 protein and 10-20 WBC. She denies any recent history of hematuria, dark urine, fever, dysuria, or cold/flu-like illness. Which of the following is the likely cause of her renal dysfunction?
| A. | Post-streptococcal glomerulonephritis |
| B. |
Lupus nephritis |
| C. |
Urinary tract infection |
| D. |
Allergic interstitial nephritis |
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