Question
A 68-year-old man experiences severe, sudden-onset chest pain radiating to the left arm with profuse sweating. He was admitted to the emergency ward. ECG was done which showed ST segment elevation in precordial leads. Patient succumbed to death after 3 hours. During the autopsy heart was immersed in triphenyl tetrazolium chloride solution. What will be the colour imparted to the viable myocardium
| A. |
Grey
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| B. |
Brick red
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| C. |
Yellow
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| D. |
White
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Show Answer
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Correct Answer � B
Explanation
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|
Answer- B
- Triphenyl tetrazolium chloride stain imparts a brick red colour to the intact non-infarcted myocardium.
- Acute Myocardial Infarction as a cause of death is diagnosed in many cases of sudden death based on the indirect evidence of critical narrowing (75%) of one or more coronary arteries. Microscopic evidence of infarction is seen in H & E stained sections only if the person has survived for a minimum period of 6 hours after sustaining a fatal ischaemic attack.
- Two methods for Postmortem Diagnosis of Early MI, viz. Triphenyl Tetrazolium Chloride (TTC) staining of slices of myocardium and Acridine Orange Fluorescent Staining of sections.
- TTC can detect MI of 4-5 hours of age and latter of around 2 hours
