Question
| A. |
Pegvisomant |
| B. |
Mecasermin |
| C. |
Tesamorelin |
| D. |
Bromocriptine |
|
Correct Answer � A Explanation |
 |
Pegvisomant is a growth hormone receptor antagonist. It is used in the treatment of acromegaly, a condition characterized by excess growth hormone production, typically due to a pituitary adenoma. Pegvisomant acts by binding to and blocking the growth hormone receptor, thereby inhibiting the effects of excess growth hormone. This antagonist action helps normalize the abnormal growth seen in acromegaly.
Mecasermin, also known as recombinant human insulin-like growth factor-1 (IGF-1). It is a medication used to treat growth hormone insensitivity or resistance by providing exogenous IGF-1 to the body.
Tesamorelin is not a growth hormone receptor antagonist either. It is a synthetic form of growth hormone-releasing hormone (GHRH) used to reduce excess abdominal fat in people with HIV-associated lipodystrophy.
Bromocriptine acts on dopamine receptors and is used for various conditions, including Parkinson’s disease and certain hormonal disorders. It does not directly target the growth hormone receptor.
