Question
What is the investigation of choice for a parathyroid adenoma?
| A. |
Tc99-Sestamibi scan |
| B. |
Sestamibi SPECT |
| C. |
USG (Ultrasound) |
| D. |
CT (Computed Tomography) |
Show Answer
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Correct Answer � A Explanation |
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For diagnosing a parathyroid adenoma, the investigation of choice is the Tc99-Sestamibi scan. This nuclear medicine scan specifically helps to localize hyperfunctioning parathyroid tissue (adenomas) due to its uptake in areas with increased mitochondrial activity, which is characteristic of parathyroid adenomas.
- Tc99-Sestamibi scan: This is the most commonly used technique to localize parathyroid adenomas pre-operatively. It is highly sensitive and specific for detecting overactive parathyroid glands.
Why Other Options Are Less Preferred:
- Sestamibi SPECT: While it can also be used, the standard Tc99-Sestamibi scan is usually sufficient for most patients. SPECT can provide three-dimensional imaging and better localization in some cases, but it is not always necessary.
- USG (Ultrasound): Ultrasound is commonly used as a complementary tool to the sestamibi scan. It helps in identifying adenomas, particularly in the neck region, but is less sensitive than sestamibi scanning.
- CT (Computed Tomography): CT scans are not typically the first-line imaging modality for parathyroid adenomas. They may be used in certain cases where other imaging modalities fail or when anatomical variations make localization difficult.
