MENINGIOMA

MENINGIOMA


                                                                MENINGIOMA

  • Meningioma are benign slow growing, encapsulated tumours arising from arachanoid meningothelial cells.
  • Seen in adults (females) & attached to dura.
  • MC primary brain tumour- meningioma > glial tumour
  • They are MC intracranial, extracranial dural based neoplasm.

Clinical features-

  • Motor deficit – 90% & sensory deficit- 60%

Histology-

a)     Syncytial – whorled cluster of cells

b)    Fibroblastic- collagen between cells

c)     Transitional  – syncytial + fibroblastic

d)    Psammomatous- psammoma bodies present

e)     Secretory- pseudopsammoma border

Clinical features-

  • Malignant meningioma are highly aggressive tumours.

Investigations-

  • Nearly all meningiomas enhance intensely following contrast administration.
  • Abnormal vascular markings
  • Enlarged foramen spinosum on the side of lesion
  • Dural tail
  • Calcification in the tumor
  • Invasion of bone cause localized bony hyperostosis/mixed osteoblastic and osteolytic response less commonly. It may show ‘sun ray spicules’ and local bone expansion with pneumatization so called ‘blistering’.
  • Signs of increased intracranial tension

 




Treatment-

  • Surgery- TOC

Exam Important

  • Meningioma are benign slow growing, encapsulated tumours arising from arachanoid meningothelial cells.
  • Seen in adults (females) & attached to dura.
  • MC primary brain tumour- meningioma > glial tumour
  • They are MC intracranial, extracranial dural based neoplasm.
  • Meningioma are benign slow growing, encapsulated tumours arising from arachanoid meningothelial cells.
  • Seen in adults (females) & attached to dura.
  • MC primary brain tumour- meningioma > glial tumour
  • They are MC intracranial, extracranial dural based neoplasm.

Clinical features-

  • Motor deficit – 90% & sensory deficit- 60%

Histology-

a)     Syncytial – whorled cluster of cells

b)    Fibroblastic- collagen between cells

c)     Transitional  – syncytial + fibroblastic

d)    Psammomatous- psammoma bodies present

e)     Secretory- pseudopsammoma border

Clinical features-

  • Malignant meningioma are highly aggressive tumours.

Investigations-

  • Nearly all meningiomas enhance intensely following contrast administration.
  • Abnormal vascular markings
  • Enlarged foramen spinosum on the side of lesion
  • Dural tail
  • Calcification in the tumor
  • Invasion of bone cause localized bony hyperostosis/mixed osteoblastic and osteolytic response less commonly. It may show ‘sun ray spicules’ and local bone expansion with pneumatization so called ‘blistering’.
  • Signs of increased intracranial tension
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