Mushroom poisoning

Mushroom poisoning

Q. 1 The drug of choice for mushroom poisoning is which of the following?

 A Atropine

 B

Carbachol

 C

Adrenaline

 D

Physostigmine

Q. 1

The drug of choice for mushroom poisoning is which of the following?

 A

Atropine

 B

Carbachol

 C

Adrenaline

 D

Physostigmine

Ans. A

Explanation:

Ans. A. Atropine

Symptoms of mushroom poisoning are due to excess of muscarine.

The polypeptides from these mushrooms are inhibitors of cellular protein synthesis and stimulate postganglionic cholinergic fibers.

Atropine sulphate is the preferred drug of choice to counteract the muscarinic effects.


Q. 2

Toxin in mushroom poisoning principally affects:

March 2011

 A

Liver

 B

Lung

 C

Bladder

 D

Nerves

Ans. D

Explanation:

Ans. D: Nerves

Toxins of mushroom (poison) are parasympathomimetic

Mushroom poisoning

  • Main sign and symptoms: Nausea, vomiting, diarrhea, bloody vomitus and stools, enlarged tender liver and jaundice, oliguria, pulmonary edema, mental confusion, convulsions, coma
  • Average fatal dose: 1/2 to 1 mushroom
  • Fatal period: 3-6 days
  • Treatment: Gastric lavage, supportive, atropine, exchange transfusion in children, charcoal hemoperfusion in adults


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