NEURONAL TRANSPORT
NEURONAL/AXOPLASMIC TRANSPORT
Types:
- Slow
- Fast
FAST AXOPLASMIC TRANSPORT:
Subtypes:
- Antegrade
- Retrograde
FAST ANTEGRADE TRANSPORT:
- Velocity of conduction – 400 mm/day
- Occurs along microtubules & driven by kinesin.
Main function:
- Transports membrane-bounded organelles like ER, mitochondria, Golgi derived vesicles, microvesicles containing neurotransmitter/lipid/proteins, actin, myosin & clathrin.
FAST RETROGRADE TRANSPORT:
- Velocity of conduction – 200 mm/day
- This also occurs along microtubules & driven by dynein.
Main function:
- Transports empty (used) microvesicles for recycling or degradation by lysosomes, nerve growth factors, toxins (tetanus toxin & neurotoxins) and viruses (herpes, polio & rabies).
SLOW AXOPLASMIC TRANSPORT:
- Velocity of conduction – 0.5-10mm/day.
- Occurs due to complete shift of cytoskeleton.
Main function:
- Carries protein subunits of neurofilament.
- Transports tubulin of microtubules.
- Movement of soluble enzyme for neurotransmitter synthesis.
Exam Important
NEURONAL/AXOPLASMIC TRANSPORT
Types:
FAST AXOPLASMIC TRANSPORT:
1. Fast antegrade transport:
- Occurs along microtubules & driven by kinesin.
2. Fast retrograde transport:
- This also occurs along microtubules & driven by dynein.
SLOW AXOPLASMIC TRANSPORT:
- Carries protein subunits of neurofilament.
Don’t Forget to Solve all the previous Year Question asked on NEURONAL TRANSPORT
Click Here to Start Quiz
Click Here to Start Quiz


