Which app has NEET PG PYQs from 2012 to 2025?

MedicoApps provides authentic NEET PG previous year questions from 2012 to 2025 with detailed explanations, clinical coverage, and offline access.

How many questions are included in MedicoApps?

MedicoApps includes over 10,000 meticulously crafted clinical and image-based questions, each with a detailed explanation covering NEET PG, NeXT PG, INI CET, and FMGE exams.

Does the MedicoApps NEET PG app support offline access?

Yes, MedicoApps is fully offline. You can study and practice previous year questions without an internet connection.

Does MedicoApps include clinical and image-based questions?

Yes, MedicoApps includes clinical and image-based questions with complete explanations and references, covering subjects tested in NEET PG.

Does MedicoApps focus on repeated concepts and high-yield topics?

Yes, MedicoApps follows an 80/20 high-yield preparation approach, emphasising repeated concepts since 60-75% of NEET PG questions come from concepts tested in past exams.

Is there an update frequency for new questions in MedicoApps?

The app is regularly updated to align with the latest NEET PG exam patterns and includes new questions as per evolving trends in medical entrance exams.

Do the questions in MedicoApps come with detailed explanations?

Yes, each question is accompanied by an explanatory note that clarifies the concept behind the answer and references relevant sources.

Which previous year exams are included in MedicoApps?

MedicoApps includes authentic previous year questions from NEET PG, NeXT PG, INI CET, and FMGE exams, spanning from 2012 to 2025.

Is MedicoApps suitable for students at different stages of NEET PG preparation?

Yes, MedicoApps is suitable for both beginners and advanced students. It offers a wide range of questions to support preparation at all stages.

Is there a money-back guarantee for MedicoApps?

Yes, MedicoApps offers a no-questions-asked 30-day money-back guarantee on all premium plans.

What is the best QBank for NEET PG?

A good NEET PG QBank should include PYQs, clinical MCQs, image-based questions, and grand tests. MedicoApps provides all these features along with offline access and explanations in one platform.

Where can I practice NEET PG previous year questions?

You can practice NEET PG previous year questions on MedicoApps, which includes 10,000+ questions from 2012 to 2025 with detailed explanations and offline support.

How can I contact MedicoApps support?

You can reach the MedicoApps customer support team through the app or the official website at medicoapps.org.

NEUROTRANSMITTERS - FUNCTIONS & MECHANISM OF ACTION IN CNS

NEUROTRANSMITTERS – FUNCTIONS & MECHANISM OF ACTION IN CNS

Q. 1 5-HIAA (Hydroxyindoleacetic Acid) is a metabilite of which of the following neurotransmitters?

A		Noradrenaline
B		Serotonin
C		GABA
D		Glutamine

Q. 2

Which of the following neurotransmitters are implicated in both mania and depression?

A		GABA & dopamine
B		Serotonin and Nor epinephrine
C		Serotonin and dopamine
D		Nor epinephrine and GABA

Q. 3

All of the following neurotransmitters are excitatory and inhibitory in function,:

A		Glycine
B		Glutamine
C		Aspartate
D		NO

Q. 4

Panic attack is associated with a disturbance in all of the following neurotransmitters except:

A		Serotonin
B		GABA
C		Glutamate
D		Dopamine, CCK, pentagastrin

Q. 5

Excitatory Neurotransmitters are :

A		Acetyl choline
B		Glycine
C		GABA
D		Glutamine

Q. 1

5-HIAA (Hydroxyindoleacetic Acid) is a metabilite of which of the following neurotransmitters?

A		Noradrenaline
B		Serotonin
C		GABA
D		Glutamine

Ans. B

Explanation:

Serotonin (5-HT) is metabilised the key enzyme Mono Amino Oxidase (MAO) and one of the main metabolite of clinical significance is 5-HIAA.

The CSF levels of 5-HIAA (Hydroxyindoleacetic Acid) is low in patients who committed suicide, in depression and violence.

It is considered to be associated with poor impulse control. It can be used to predict violent suicide. It is not known to be reduced in OCD.

Ref: Kaplan & Sadock’s Synopsis of Psychiatry, By Benjamin J Sadock, M.D., Harold I. Kaplan, Virginia A Sadock, M.D, 10th Edition, Page : 265

Q. 2 Which of the following neurotransmitters are implicated in both mania and depression?

A		GABA & dopamine
B		Serotonin and Nor epinephrine
C		Serotonin and dopamine
D		Nor epinephrine and GABA

Ans. B

Explanation:

Increase of Norepinephrine (noradrenaline) and serotonine levels causes mania and reverse cause depression.

Hence, the treatment of depression involves increasing serotonin levels and noradrenaline levels.

Antidepressants could trigger mania or hypomania due to excessive increase in the neurotransmitters in prone individuals.

Mania or hypomania induced by anti-depressants is called Bipolar III.

Q. 3

All of the following neurotransmitters are excitatory and inhibitory in function,:

A		Glycine
B		Glutamine
C		Aspartate
D		NO

Ans. A

Explanation:

Glycine has both excitatory and inhibitory effects in the CNS.

When it binds to NMDA receptors, it makes them more sensitive to the actions of glutamate.

It is also responsible in part for direct inhibition, primarily in the brainstem and spinal cord.

Like GABA, it acts by increasing Cl- conductance. Its action is antagonized by strychnine.

Glutamate and aspartate are found in very high concentrations in brain, and both amino acids have powerful excitatory effects on neurons in virtually every region of the CNS.

NO acts as a signal by which postsynaptic neurons communicate with presynaptic endings to enhance release of glutamate.

Ref: Barrett K.E., Barman S.M., Boitano S., Brooks H.L. (2012). Chapter 7. Neurotransmitters & Neuromodulators. In K.E. Barrett, S.M. Barman, S. Boitano, H.L. Brooks (Eds), Ganong’s Review of Medical Physiology, 24e.

Q. 4 Panic attack is associated with a disturbance in all of the following neurotransmitters except:

A		Serotonin
B		GABA
C		Glutamate
D		Dopamine, CCK, pentagastrin

Ans. C

Explanation:

Ans:C-Glutamate

Panic disorder is associated with noradrenaline (norepinephrine), cholecystokinin (CCK)- pentagastrin /tetrapeptide (administration or agonism of both); GABA (antagonism) and serotonin (decrease).
The neurotransmitters serotonin, dopamine, norepinephrine, and gamma-aminobutyric acid (GABA) are specifically believed to be linked to mood and anxiety disorders.
These neurotransmitters are in charge of regulating various body functions and emotions.

Q. 5

Excitatory Neurotransmitters are :

A		Acetyl choline
B		Glycine
C		GABA
D		Glutamine

Ans. D

Explanation:

D i.e. Glutamate

NEUROTRANSMITTERS – FUNCTIONS & MECHANISM OF ACTION IN CNS

NEUROTRANSMITTERS – FUNCTIONS & MECHANISM OF ACTION IN CNS

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