PEYRONIE’S DISEASE
PEYRONIE’S DISEASE (PENILE FIBROMATOSIS/ INDURATION- PENIS PLASTICA)
- It is a development of fibrous tissue plaque on the covering of corpus cavernosum involving tunica albuginea which may later calcify or ossify.
- Palmar fibromatosis + plantar fibromatosis + penile fibromatosis = superficial fibromatosis
ETIOLOGY
- Associated with-
a) Dupuytren’s contracture (plamar fibromatosis)
b) Retroperitoneal fibrosis
c) Plantar facitis
- Trauma
- Venereal disease
CLINICAL FEATURES-
- Painful erection, curvature of penis and poor erection distal to involved area
- Palpable induration or mass present on dorsolateral aspect of the penis
- Later erectile dysfunction, penile shortening
- Indurated plaque in the penis
- Spontaneous regression occurs in 50% of the cases.
TREATMENT-
- Drugs- steroids, Vitamin E, tsmoxifen, terfenadine and fexafenadine (not very effective)
- Intralesional injection- verapamil
- Surgery-
a) Excision and placation to opposite side- fitzpatric
b) Multiple incisions over fibrous plaque and temporal fascia bridging- Gelhard’s operation
Exam Important
ETIOLOGY
- Associated with-
a) Dupuytren’s contracture (plamar fibromatosis)
b) Retroperitoneal fibrosis
c) Plantar facitis
- Trauma
- Venereal disease
CLINICAL FEATURES-
- Painful erection, curvature of penis and poor erection distal to involved area
- Palpable induration or mass present on dorsolateral aspect of the penis
- Later erectile dysfunction, penile shortening
- Indurated plaque in the penis
- Spontaneous regression occurs in 50% of the cases.
TREATMENT-
- Drugs- steroids, Vitamin E, tsmoxifen, terfenadine and fexafenadine (not very effective)
- Intralesional injection- verapamil
- Surgery-
a) Excision and placation to opposite side- fitzpatric
b) Multiple incisions over fibrous plaque and temporal fascia bridging- Gelhard’s operation
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