PINGUECULA & PTERYGIUM
PINGUECULA
- Degenerative condition of conjunctiva.
- Characterized by triangular yellowish white patch on the bulbar conjunctiva near the limbus.
- The apex of triangle being away from the cornea & affects the nasal side first, then the temporal.
- It is due to hyaline infiltration & elastotic degeneration of sub-mucous tissue.
- Usually found in elderly people, especially those exposed to strong sunlight, dust, wind etc.
- Considered as a precursor of pterygium frequently follows a pinguecula.
- It requires no treatment.

PTERYGIUM
- Pterygium is a non- cancerous (non-neoplastic) growth of conjunctiva.
- Characterized by a wing-shaped fold of conjunctiva upon the cornea from either side within the interpalpebral fissure.
- Pterygium is always situated in the palpebral aperture.
- Pathologically Pterygium is a degenerative & hyperplastic condition of conjunctiva.
- The subconjunctival tissue undergoes elastotic degeneration & proliferates as vascularised granulation tissue under the epithelium, which ultimately encroaches the cornea.
- The corneal epithelium, Bowman’s layer & stroma are destroyed.
ETIOLOGY & CLINICAL FEATURES
- More common in people with excess outdoor exposure to sunlight (UV rays) dry, heat, high wind & abundance of dust.
- Clinically, presents as a triangular fold of conjunctiva encroaching the cornea in the area of palpebral aperture, usually on the nasal side.
- Other findings are stocker’s line (deposition of iron).
- Pterygium is an asymptomatic condition in the early stages, except for cosmetic intolerance.
- Visual disturbance or corneal astigmatism ma occur.
- Visual disturbances are due to encroachment of pterygium on pupillary area or corneal astigmatism.
- Occasionally diplopia may occur due to limitation of ocular movements.

TREATMENT
- Asymptomatic pterygium which is not progressive is best left alone.
- Surgical excision is the only satisfactory treatment & is indicated for:
- Cosmetic reasons
- Continued progression threatening to encroach onto the papillary area
- Diplopia due to interference in ocular movement
- Simple excision (‘bare sclera’ technique) is associated with high recurrence rate (upto 80%) that may be more aggressive than the initial lesion.
- Thus conjunctival autografting is currently most popular approach.
- Adjunctive treatment with mitomycin c, beta-irradiation, & amniotic membrane patch grafting can also be used for aggressive lesions.
Exam Important
PTERYGIUM
- Pterygium is Connective tissue proliferation.
- Cause of blindness in pterygium is Astigmatism.
- Drug used to avoid recurrence of pterygium is Mitomycin C.
- The histology of pterygium includes Elastotic degeneration.
- Lacy white lesion in mouth with pterygium is seen in Lichen planus.
PINGUECULA
- Degenerative condition of conjunctiva.
- Characterized by triangular yellowish white patch on the bulbar conjunctiva near the limbus.
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