Salvage pathway of purine nucleotide synthesis
| A | Hypoxanthine and Xanthine | |
| B | Hypoxanthine andAdenine | |
| C | Adenine and Guanine | |
| D | Xanthine and Guanine |
| A | Hypoxanthine and Xanthine | |
| B | Hypoxanthine andAdenine | |
| C | Adenine and Guanine | |
| D | Xanthine and Guanine |
Hypoxanthine andAdenine
Which among the following substrates are needed for the purine salvage pathway?
| A |
Hypoxanthine and Xanthine |
|
| B |
Hypoxanthine and Adenine |
|
| C |
Adenine and Guanine |
|
| D |
Xanthine and Guanine |
Salvage pathway of purine biosynthesis is important for ‑
| A |
Liver |
|
| B |
RBCs |
|
| C |
Kidney |
|
| D |
Lung |
Purine nucleotide synthesis occurs by two pathways :
1.De novo synthesis
2.Salvage pathway
Liver is the major site of purine nucleotide biosynthesis (de novo).
Certain tissues cannot synthesize purine nucleotides by de novo patyway, e g. brain, erythrocytes and polymorphonuclear leukocytes.
These are dependent on salvage pathway for synthesis of purine nucleotides by using exogenous purines, which are formed by degradation of purine nucleotides synthesized in liver.
| A | Brain | |
| B |
Liver |
|
| C |
RBC |
|
| D |
Leukocytes |
Purine nucleotide synthesis occurs by two pathways :-
1.De novo synthesis
2.Salvage pathway
Liver is the major site of purine nucleotide biosynthesis (de novo).
Certain tissues cannot synthesize purine nucleotides by de novo patyway, e g. brain, erythrocytes and polymorphonuclear leukocytes.
These are dependent on salvage pathway for synthesis of purine nucleotides by using exogenous purines, which are formed by degradation of purine nucleotides synthesized in liver.
| A | Brain | |
| B |
Liver |
|
| C |
RBC |
|
| D |
Leukocytes |
Purine nucleotide synthesis occurs by two pathways :
- De novo synthesis
- Salvage pathway
The liver is the major site of purine nucleotide biosynthesis (de novo).
Certain tissues cannot synthesize purine nucleotides by the de novo pathway, eg. brain, erythrocytes, and polymorphonuclear leukocytes.
These are dependent on the salvage pathway for the synthesis of purine nucleotides by using exogenous purines, which are formed by degradation of purine nucleotides synthesized in the liver
