Sickle cell crisis

Sickle cell crisis

→ It is characterized by intense bone pain due to intense sequestration of sickled erythrocytes & infarction in various organs.

→ Pregnancy can precipitate sickle cell crisis in both women with sickle cell trait and sickle cell disease.


→ IV fluids, O2

→ Epidural analgesia

→ Antibiotics

→ Thromboprophylaxis

Note: Red cell transfusion after the onset of pain do not have much benefit but prophylactic transfusions before the crisis, helps in decreasing the pain and shortening the duration of crisis.

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