Sphingophospholipids
| A | Carnitine | |
| B |
Ceramide |
|
| C |
Diacylglycerol |
|
| D |
Sphingomyelin |
Which of the following structures is common to all sphingolipids?
| A |
Carnitine |
|
| B |
Ceramide |
|
| C |
Diacylglycerol |
|
| D |
Sphingomyelin |
| A |
Lecithine |
|
| B |
Cardiolipin |
|
| C |
Sphingomyelin |
|
| D |
Cellulose |
Sphingomyelin has got sphingosine alcohol, not the glycerol. Lecithin & cardiolipin has got glycerol in it and they are membrane phospholipid.
Glycosphingolipidis made up of:
| A |
Glucose |
|
| B |
Fatty acids |
|
| C |
Sphingosine |
|
| D |
All Correct |
A, B, C i.e. Glucose, Sphingosine, Fatty acids
Glycosphingolipid = Ceramide (Sphingosine / amino alcohol + Fatty acid) + Mono/oligo saccharide like glucose, galactose. Ganglioside (acidic glycosphingolipid) = Ceramide + Oligosaccharide + NANA (N-acetylneuraminic acid or sialic acid)
– Glyco-sphingolipid is made up of ceramide (which is a long chain fatty acid attached to amino group of sphingosine through an amide linkage i.e. = sphingosine/ amino alcohol + Fatty acid) attached directly to mono /oligo saccharide
(polar head) by an 0-glycosidic bond. Glycosphingolipids differ from sphingomyelin (phospho- sphingolipid) in that they do not contain phosphate (polar group); and differ from glycerophospholipids (phosphoglycerides) that they do not contain glycerol.
Ganglioside (acidic, negatively charged glyco-sphingolipid) contain sphingosine alcohol (4 sphingenine) 1 molecule, long chan fatty acid (1 mol), Oligosaccharide polar head and 1 or more residues of N- acetylneurminic acid (Neu 5 Ac), a sialic acid (often simply called sialic acid) giving it a negative charge, at termini. Ganglioside do not contain glycerol and phosphateQ.
Ceramide containing sphingosine amino alcohol is present in all sphingolipids (ie. phospho & glyco- sphingolipids)Q.

