Structure Of Immunoglobulin

Ans. is ‘b & c’ i.e., IgD & IgM

.   B cells display immunoglobulin molecules on their surface. These immunoglobulins serve as receptors for a specific antigen, so that each B cell can respond to only one antigen or a closely related group of antigens. All immature B cells carry Ig M immunoglobulins on their surface and most also carry Ig D.

.  Combination of cell membrane bound Ig M or Ig D with the corresponding antigen leads to specific stimulation of the B cells – either activation and cloning to produce antibody, or suppression.

.  B cells also have surface receptors for the Fc portion of immunogloblins and for several complement components.

Ans. is ‘c’ i.e., 2 Light chains, 2 Heavy Chains

Ans. is ‘d’ i.e., Fc fragment

. Fc fragment is composed of the carboxyterminal. It determines the biological activity such as complement fixation, placental transfer, skin fixation and catabolic rate.

• CH-2 of Ig G and C_H, of IgM bind to C₁q portion of CI.

Ans. is ‘b’ i.e., H chain

Ans. is ‘b’ i.e., H chain

.       The H chain has molecular weight of 50, 000.

.       The L chain has molecular weight of 25, 000.

Ans. is ‘b’ i.e., Hypervariable region

. Ans. is ‘a’ i.e., IgG and IgM