APLA

Antiphospholipid antibody syndrome-Management

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 Antiphospholipid antibody syndrome-Management If APLA is diagnosed based on H/O Abortion then aspirin along with low molecular weight heparin has to be given Aspirin: • Aspirin low doses= 50-100mg (80mg) • Started-Urine Pregnancy Test (UPT) +ve • Continued throughout Pregnancy • Stopped 4-6 days before labor Heparin: Started- Only after confirmation of IU pregnancy […]

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Antiphospholipid antibody syndrome-Diagnosis

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Antiphospholipid antibody syndrome-Diagnosis Clinical diagnosis: 1. Arterial/ Venous Thrombosis (Superficial/Deep) ≥3 losses in <10 weeks 3. ≥1 loss in >10 weeks of morphologically normal fetus. At least 1 Preterm delivery secondary to severe PIH/Uteroplacental insufficiency Lab Findings: Presence of Lupus Anticoagulant (LAC) Presence of IgM / IgG Cardiolipin Antibody Any of these should beresent@2occasions12wksapart Presence

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