Tag: cerebral blood flow

Fluid compartment of CNS


Fluid compartment of CNS


Main fluid components – Cerebrospinal Fluid & Cerebral blood flow

Functionality:

• Lubrication by CSF

• Nutrition by cerebral blood flow

Cerebrospinal Fluid:

→ Normal Volume = 150 mL; Normal CSF pressure = 70 -180 mm H2O.

→ Rate of CSF production = 550 mL/day; Recycling rate = 3.7 times/day

→ Site of production = CHOROID PLEXUS; Absorption site = ARACHNOID VILLI

→ Regulation occurs at level of absorption.

Regulation of cerebral blood flow


Regulation of cerebral blood flow


Major Regulating factors – Blood pressure, PCO2 & Temperature.

The mechanism involved in each one of the factors are:

1.Blood pressure Fluctuation Bt. 65 – 140 mm Hg NO CHANGE in blood flow

AUTOREGULATION

2. PCO2

↑ PCO2 -↑ Blood Flow

3. Temperature

On ↓ Body Temp. by 1° C -↓ cerebral flow by 7% – INDUCED HYPOTHERMIA in

neurosurgical procedures – Minimizes blood loss

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