Regulation of cerebral blood flow
Major Regulating factors – Blood pressure, PCO2 & Temperature.
The mechanism involved in each one of the factors are:
1.Blood pressure Fluctuation Bt. 65 – 140 mm Hg NO CHANGE in blood flow
AUTOREGULATION
2. PCO2
↑ PCO2 -↑ Blood Flow
3. Temperature
On ↓ Body Temp. by 1° C -↓ cerebral flow by 7% – INDUCED HYPOTHERMIA in
neurosurgical procedures – Minimizes blood loss