Tag: energetics

Palmitic Acid-Energetics


Palmitic Acid-Energetics


Step 1 – Activation of Palmitic Acid [Loss of 2 ATP]

Step 2 – Break Down of Palmitic Acid into Acetyl CoA – Total 7 Cycles

  • Each Cycle Produce 1 Mole of Each NADPH + FADH = 2.5 + 1.5 ATP = 4 ATP
  • Total Energy Produced by this Step = 7 X 4 = 28 ATP

Fate 1– Generation of ATP by taking Acetyl CoA to Krebs’s Cycle [Total 8 Acetyl CoA]

  • Total Energy Produced by this Step = 8 X 10 = 80 ATP

Fate 2– Conversion of Acetyl CoA to Acetoacetate

  • Total Energy Produced / Lost by this Step = Zero

Fate 3– Conversion of Acetyl CoA to Beta Hydroxy Butyrate

  • Loss of 1 Mole of NADPH = 4 X 2.5 = 10 ATP Lost

Fate 1 = 80 + 28 – 2 = 106 ATP

Fate 2 = 28 – 2 = 26 ATP

Fate 3 = 28 – 2 – 10 = 16 ATP

Ketone Body-Energetics


Ketone Body-Energetics


→ Each Acetyl CoA Produces 10 ATP

→ Conversion of Acetoacetate to Acetoacetyl CoA leads to Loss of an ATP Production Step in TCA Cycle

→ Conversion of Beta Hydroxy Butyrate to Acetoacetate generate 1 Mol of NADPH+H

Acetoacetate = (2 X 10)- 1 ATP = 19 ATP

Beta OH Butyrate = (2 X 10)- (1 ATP) + (2.5 ATP) = 21.5 ATP

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