The cells marked by a “black arrow” in the blood smear of a patient given below are most commonly seen in cases of ?
A. Sickle Cell Anemia.
C. Myeloproliferative disorders.
D. Both A & C.
The cells marked by a black arrow in the blood smear of a patient given above represents Tear-Drop Cells.
Ans: D. Sickle Cell Anemia,Thalassemia,Myeloproliferative disorders.
Tear Drop Cell
- A deformed RBC which is tugged to a nipple at one end, having squeezed through a reticuloendothelial system with increased connective tissue.
It is found in conditions as follows:
- Myelofibrosis, and other reticuloendothelial replacement disorders that compromise the bone marrow space,causing splenic overload or decreased functional splenic tissue e.g., megaloblastic anaemia, hereditary elliptocytosis,anaemia of renal disease, haemolytic anaemias, sickle cell anaemia, thalassemia, and bone marrow infiltration by haematologic and non-haematologic malignancies.