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Schizophrenia-Treatment

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Schizophrenia-Treatment Pharmacological treatment of schizophrenia includes antipsychotics/neuroleptics. Both typical and atypical antipsychotics are used Typical antipsychotics (1st gen): Acts Via D2 Receptor Antagonism Effective Against Positive Symptoms Minimal Effect on Negative Symptoms Causes More Extrapyramidal Side Effects Atypical antipsychotics (1st gen): Acts Via D2 & 5HT 2 Receptor Antagonism Effective Against (+) and (-) Symptoms […]

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Schizophrenia-Prognosis

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Schizophrenia-Prognosis The prognostic factors of schizophrenia are: Good Prognostic factors: Acute / Abrupt Onset Late Onset [Age > 35 Yrs.] Catatonic & Paranoid Female Sex Prominent Positive Symptoms Affective Symptoms [Depression] Family History of Mood Disorder Poor prognostic factors: Insidious Onset Early Onset [Age > 20 Yrs.] Simple, Disorganized, Undifferentiated Male Sex Prominent Negative Symptoms

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Schizophrenia-Motor symptoms

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Schizophrenia-Motor symptoms The symptoms of schizophrenia are divided into: Positive Negative Disorganization Motor Motor Symptoms: Catatonia-Term given by Karl Kahl Baum Stupor-Extreme hypoactivity or immobility and minimal response to stimuli Excitement-Extreme Hyperactivity which is usually not goal directed Posturing / Cataplexy-Spontaneous maintenance of posture for long periods of time Waxy flexibility-Passive movements by examiner have

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Etiopathogenesis of schizophrenia-Neuropathological factors

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Etiopathogenesis of schizophrenia-Neuropathological factors The etiopathogenesis of schizophrenia consists of following factors: Genetic Biochemical Neuropathological Neuropathological Factors: Cerebral Ventricle s – ↓ Cerebral Grey Matter and ↑ Lateral and 3rd Ventricle Limbic System – ↓ Hippocampus, ↓ Amygdala, ↓ Para hippocampal Gyrus Abnormalities of Prefrontal Cortex, basal ganglia and cerebellum Neuronal Loss in MEDIAL DORSAL

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