Retinoblastoma

Differential diagnosis of leucocoria

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 Differential diagnosis of leucocoria 1. Retinoblastoma 2. Congenital Cataract 3. Persistent Hyperplastic primary vitreous [PHPV] Most difficult to d/d from Retinoblastoma FATES OF VITREOUS: Before Birth After Birth •         Primary Vitreous → Disappears (retention → PHPV) •         Secondary Vitreous → Normal •         Tertiary Vitreous → Zonules D/D of PHPV from RB: PHPV: Always U/L […]

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Retinoblastoma-Treatment

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 Retinoblastoma-Treatment The treatment of retinoblastoma includes the following: Focal- Cryotherapy Laser photocoagulation Trans pupillary Thermotherapy Systemic- This involves chemotherapy, which is further divided into the following Intravenous: Success rates > 95% [VEC] – 6 cycles S/E – deafness Intravitreal: DOC- MELPHALAN Intraarterial: Into Ophthalmic Artery MELPHALAN TOPOTECTAN CARBOPLATIN Enucleation: Advanced intra ocular RB with

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