Tuberous Sclerosis

Tuberous Sclerosis Q. 1 Earliest feature of tuberous sclerosis is?   A Facial angiofibroma  B Shagreen patch  C Ash leaf spot  D Gingival fibroma Q. 1 Earliest feature of tuberous sclerosis is?   A Facial angiofibroma  B Shagreen patch  C Ash leaf spot  D Gingival fibroma Ans. C Explanation: Ash leaf spot REF: Harrison’s 18th ed chapter […]

Tuberous Sclerosis TUBEROUS SCLEROSIS (SYN. BOURNEVILLES DISEASE) TSC is now known to be an Autosomal dominant disorder affecting cellular differentiation, proliferation, and migration early in development, resulting in a variety of hamartomatous lesions that may affect virtually every organ system of the body. TSC is caused by a mutation of either of two genes, TSC1