THALASSEMIA

• Thalassemia is an autosomal recessive hereditary disorder.
• It is caused by mutation that decreases synthesis of α and β- globin chains.
• There is deficiency of haemoglobin & red blood cells.
• Seen in Mediterranean countries.
• Thalassemia is genetically transmitted disorders.
• α- chain genes are located on chromosome 16.
• β- chain genes are located on chromosome 11.

Classification-

• Thalassemias are classified into-

1. α- thalassemias
2. β- thalassemias

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