Vibrio Cholerae Management
| A | Tetracycline | |
| B |
Co-trimoxazole |
|
| C |
Doxycycline |
|
| D |
Furazolidone |
Antibiotic treatment of choice for treating cholera in an adult is a single dose of:
| A |
Tetracycline |
|
| B |
Co-trimoxazole |
|
| C |
Doxycycline |
|
| D |
Furazolidone |
Doxycycline – antibiotic of choice for adults only single dose suffices.
| A |
Tetracycline |
|
| B |
Doxycycline |
|
| C |
Furazolidone |
|
| D |
Cotrimoxazole |
Ans. is ‘c’ i.e., Furazolidone
Cholera vaccine effectiveness is –
| A |
20% for 12 months |
|
| B |
50% for 12 months |
|
| C |
20% for 36 months |
|
| D |
50% for 36 months |
Ans. is ‘b’ i.e., 50% for 12 months
Chemoprophy laxis with tetracycline is useful in which of the following ?
| A |
Cholera |
|
| B |
Brucellosis |
|
| C |
Meningitis |
|
| D |
Leptospirosis |
Ans. is ‘a’ i.e., Cholera
o Tetracycline is the drug of choice for chemoprophylaxis in cholera and plague.
Which is cholera vaccine –
| A |
Ty21 A |
|
| B |
HGD -103 |
|
| C |
WC-rBS |
|
| D |
None |
Ans. is ‘c’ i.e., WC-r BS
Cholera Vaccine
Killed vaccines
Dukoral (WC-rBS)
Sanchol and mORC VAX
| A | Doxycycline 300 mg OD | |
| B |
Cephalosporin |
|
| C |
Streptomycin |
|
| D |
Cotrimexazole |
Ans. is ‘a’ i.e., Doxycyline 300 mg OD
Oral cholera vaccine is effective for:
September 2005
| A |
6 months |
|
| B |
12 months |
|
| C |
2 years |
|
| D |
3 years |
Ans. D: 3 years
Injectable vaccine is effective for 3-6 months and protective value is about 50%.
Proguanil and antibiotics should be avoided from one week before and one week after the administration of the live oral attenuated vaccine
| A |
To control epidemics |
|
| B |
For travellers |
|
| C |
In endemic areas |
|
| D |
In Neonates |
Ans. is ‘c’ i.e., In endemic areas
Cholera vaccination should be considered in areas where cholera is endemic.
However, it should always be done in conjunction with implementation of safe water, sanitation and hygiene promotion programme.
In resource poor areas, vaccination should be targeted at children aged 2 years.
Cholera vaccine has not been recommended in outbreak/epidemic settings or complex humanitarian emergencies because of the logistical challanges of administering 2-dose vaccine, and concern that long-scale vaccination would divert limited resources from higher priority measures.
As it does not prevent epidemic cholera transmission, it is not recommended for general population.
Cholera transmission is not recommended for travelers, as counseling about risk avoidance is more cost effective than vaccination.

