Vibrio Cholerae Management

Vibrio Cholerae Management

Q. 1 Antibiotic treatment of choice for treating cholera in an adult is a single dose of:

 A Tetracycline

 B

Co-trimoxazole

 C

Doxycycline

 D

Furazolidone

Q. 1

Antibiotic treatment of choice for treating cholera in an adult is a single dose of:

 A

Tetracycline

 B

Co-trimoxazole

 C

Doxycycline

 D

Furazolidone

Ans. C

Explanation:

Doxycycline – antibiotic of choice for adults only single dose suffices.

TMP-SMX – antibiotic of choice for children.
Furazolidone – antibiotic of choice for pregnant women.
 
Ref: Park’s Textbook Of Preventive And Social Medicine By K. Park, 19th Edition, Page 193; Park’s Textbook Of Preventive And Social Medicine By K. Park, 18th Edition, Page 181

Q. 2 The drug of choice for treating cholera in pregnant women is –

 A

Tetracycline

 B

Doxycycline

 C

Furazolidone

 D

Cotrimoxazole

Ans. C

Explanation:

Ans. is ‘c’ i.e., Furazolidone 


Q. 3

Cholera vaccine effectiveness is –

 A

20% for 12 months 

 B

50% for 12 months

 C

20% for 36 months

 D

 50% for 36 months

Ans. B

Explanation:

Ans. is ‘b’ i.e., 50% for 12 months 


Q. 4

Chemoprophy laxis with tetracycline is useful in which of the following ?

 A

Cholera

 B

Brucellosis

 C

Meningitis

 D

Leptospirosis

Ans. A

Explanation:

Ans. is ‘a’ i.e., Cholera 

o Tetracycline is the drug of choice for chemoprophylaxis in cholera and plague.


Q. 5

Which is cholera vaccine –

 A

Ty21 A

 B

HGD -103

 C

WC-rBS

 D

None

Ans. C

Explanation:

Ans. is ‘c’ i.e., WC-r BS 

Cholera Vaccine

Killed vaccines

Dukoral (WC-rBS)

Sanchol and mORC VAX

          


Q. 6 Cholera prophylaxis is by –

 A Doxycycline 300 mg OD 

 B

Cephalosporin

 C

Streptomycin

 D

Cotrimexazole

Ans. A

Explanation:

Ans. is ‘a’ i.e., Doxycyline 300 mg OD 


Q. 7

Oral cholera vaccine is effective for:       

September 2005

 A

6 months

 B

12 months

 C

2 years

 D

3 years

Ans. D

Explanation:

Ans. D: 3 years

Oral vaccine is effective for at least 3 years.

Injectable vaccine is effective for 3-6 months and protective value is about 50%.

Proguanil and antibiotics should be avoided from one week before and one week after the administration of the live oral attenuated vaccine


Q. 8 Cholera vaccination is indicated ‑

 A

To control epidemics

 B

For travellers

 C

In endemic areas

 D

In Neonates

Ans. C

Explanation:

Ans. is ‘c’ i.e., In endemic areas

Cholera vaccination should be considered in areas where cholera is endemic.

However, it should always be done in conjunction with implementation of safe water, sanitation and hygiene promotion programme.

In resource poor areas, vaccination should be targeted at children aged 2 years.

Cholera vaccine has not been recommended in outbreak/epidemic settings or complex humanitarian emergencies because of the logistical challanges of administering 2-dose vaccine, and concern that long-scale vaccination would divert limited resources from higher priority measures.

As it does not prevent epidemic cholera transmission, it is not recommended for general population.

Cholera transmission is not recommended for travelers, as counseling about risk avoidance is more cost effective than vaccination.



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