Vitamin B7 & Deficiency

Vitamin B7 & Deficiency


VITAMIN B7 (BIOTIN)

  • Also called as anti-egg white injury factor or Vitamin H.
  • Synthesized by intestinal flora.
  • Reactive form is CarboxyBiocytin.
  • Biotin serves prosthetic group for carboxylation reaction.
  • Biotin acts as a coenzyme-
  1. Acetyl CoA Carboxylase
  2. Propionyl CoA carboxylase
  3. Pyruvate carboxylase
  • Biotin antagonist- Avidin (raw white egg), Streptavidin

Biotin Deficiency-

  • Depression, Hallucination
  • Anorexia
  • Seborrheic and erythematous rash near nose, eyes, mouth.
  • Alopecia

Exam Important

  • Also called as anti-egg white injury factor or Vitamin H.
  • Synthesized by intestinal flora.
  • Reactive form is CarboxyBiocytin.
  • Biotin serves prosthetic group for carboxylation reaction.
  • Biotin antagonist- Avidin(raw white egg), Streptavidin
  • Biotin acts as a coenzyme

a) Acetyl CoA Carboxylase

b) Propionyl CoA carboxylase

c) Pyruvate carboxylase

Biotin Deficiency-

  • Depression, Hallucination
  • Anorexia
  • Seborrheic and erythematous rash near nose, eyes, mouth.
  • Alopecia
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