Question
Phosphorylation of amino acid is done by:
A. Serine
B. Tyrosine
C. Leucine
D. a and b both
Show Answer
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Correct Answer » D
Explanation
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Selective phosphorylation, specific for serine & tyrosine residue or threonine and subsequent dephosphorylation is catalyzed by protein kinase & phosphatase.
In humans, the activity of many enzymes is regulated by covalent modification such as ATP dependent phosphorylation & subsequent dephosphorylation. The ease of interconversion of enzymes between their phospho- and dephospho- forms accounts, in part, for the frequency with which phosphorylation-dephosphorylation is utilized as a mechanism for regulatory control.