Image Based Question-64916

A 45 yr old female showed these cells and on direct immunofluoroscence showed intercellular IgG deposits in the epidermis. The most probable diagnosis is:

A. Bullous Pemphigoid

B. Stevens Johnson syndrome

C. Pemphigus vulgaris

D. Herpes simplex 1 infection

Correct Answer » C Explanation

This image shows Acontholytic cells in pemphigus vulgaris

Recurrent, painful oral lesions and cutaneous lesions in the form of flaccid bullae are characteristic of phemphigus vulgaris

Positive Tzanck smear, IgG deposits on direct immunofluoroscence positive nikolsky’s sign are features of phemphigus vulgaris.