Image Based Question-65016

A patient presented with the following after irritation on the skin.Which of the following cells is involved in this condition?

A. Eosinophils

B. Basophils

C. Mast Cells

D. All of the above

Correct Answer » C Explanation

Ans:C.)Mast Cells.

The patient in question is suffering from Urticaria Pigmentosa.

• Urticaria pigmentosa (also known as generalized eruption of cutaneous mastocytosis (childhood type)
• Urticaria pigmentosa is characterized by excessive amounts of mast cells in the skin.
• Red or brown spots are often seen on the skin, typically around the chest and forehead.
• These mast cells, when irritated (e.g. by rubbing the skin, heat exposure), produce too much histamine, triggering an allergic reaction that leads to hives localized to the area of irritation, sometimes referred to as Darier’s sign.