Question
Platelet adhesion to this structure occur via:
A. Factor VIII
B. Factor IX
C. Fibronectin
D. Fibronectin
Show Answer
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Correct Answer » C
Explanation
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This structure is collagen
Platelet adhesion to collagen occurs via von-Willebrand factor)
Endothelial injury allows platelets to contact the underlying extracellular matrix; subsequent adhesion occurs through interactions with von Willebrand factor (vWF), which is a product of normal endothelial cells and an essential cofactor for platelet binding to matrix elements.
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