Question
Identify the material marked by a “red arrow” in the renal biopsy of a patient given below?
A. Amyloid.
B. Carbohydrates.
C. Fats.
D. None of the above.
Show Answer
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Correct Answer » A
Explanation
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The material marked by a red arrow in the renal biopsy of a patient represented above is amyloid.By light microscopy, as represented above amyloid appears as an amorphic, eosinophilic, PAS negative or scantly positive, extracellular substance.
Renal biopsy is fundamental because the demonstration by histology of amyloid deposition is necessary and the tissue most frequently involved by amyloidosis is the kidney. Depending on peptide subunit deposition, the two most frequent types of amyloidosis have been defined, AL and AA, that can be differentiated using histochemistry and immuno-histochemistry techniques.
