Question
True about this fluid shown in this image
A. Used for treatment of antithrombin-3 deficiency.
B. Used for treatment of Vit-K deficiency.
C. Used for replacing factor VIII & IX, if deficiency.
D. a and b.
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Correct Answer » D Explanation |
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This flluid is fresh frozen plasama
Ans. is D- ‘a’ i.e., Used for treatment of antithrombin-3 deficiency; ‘b’ i.e., Used for treatment of VitK deficiency
Fresh frozen plasma (FFP)
- FFP is defined as the fluid portion of human blood that has been centrifuged, separated, and frozen solid at -18°c within 6 hours.
FFP contains stable coagulation factors and plasma proteins : ‑
- Fibrinogen
- Albumin & Immunoglobulin
- Factor II, V, VII, IX, X, XI
- Antithrombin
- Protein C, S.
Indications for the use of FFP include:
- Management of patients with selected coagulation factor deficiencies for which no specific coagulation concentrates are available (i.e., factors II (2), V (5), VII (7), X (10), XI (11), Proteins C or S*.
- It plays an important role in therapeutic management when overt bleeding is present or anticipated in DIC patients with disturbed coagulation .
- Reversal of warfarin effect
- Use in antithrombin III deficiency
- Treatment of immunodeficiencies . However, the development of a purified immune globulin for intravenous use largely has replaced Fresh frozen plasma
- Treatment of thrombotic thrombocytopenic purpura