Image Based Question-65414

True about this fluid shown in this image

A. Used for treatment of antithrombin-3 deficiency.

B. Used for treatment of Vit-K deficiency.

C. Used for replacing factor VIII & IX, if deficiency.

D. a and b.

Correct Answer » D Explanation

This flluid is fresh frozen plasama

Ans. is D- ‘a’ i.e., Used for treatment of antithrombin-3 deficiency; ‘b’ i.e., Used for treatment of Vit­K deficiency

Fresh frozen plasma (FFP)

• FFP is defined as the fluid portion of human blood that has been centrifuged, separated, and frozen solid at -18°c within 6 hours.

FFP contains stable coagulation factors and plasma proteins : ‑

1. Fibrinogen 
2. Albumin & Immunoglobulin
3. Factor II, V, VII, IX, X, XI
4. Antithrombin 
5. Protein C, S.

Indications for the use of FFP include:

• Management of patients with selected coagulation factor deficiencies for which no specific coagulation concentrates are available (i.e., factors II (2), V (5), VII (7), X (10), XI (11), Proteins C or S*.
• It plays an important role in therapeutic management when overt bleeding is present or anticipated in DIC patients with disturbed coagulation .
• Reversal of warfarin effect
• Use in antithrombin III deficiency
• Treatment of immunodeficiencies . However, the development of a purified immune globulin for intravenous use largely has replaced Fresh frozen plasma
• Treatment of thrombotic thrombocytopenic purpura