Image Based Question-65446

The cell marked by a “black arrow” in the blood smear of a patient below are most commonly seen in cases of?

A. Liver diseases.

B. Sickle cell anaemia.

C. G6PD deficiency.

D. All of the above.

Correct Answer » B Explanation

Ans: B. Sickle Cell Anemia

in the image,the arrow is pointing towards the Sickle Cell.

Sickle cells (drepanocytes)

• It used to indicate sickle-like forms of erythrocytes (crescent-shaped, irregular spines, filaments, holly-leaf appearance).
• It is noted when RBC containing HbS are subjected to reduction in oxygen tension or pH.
• Sickle cell disease (SCD) describes a group of inherited red blood cell disorders. People with SCD have abnormal hemoglobin, called hemoglobin S or sickle hemoglobin, in their red blood cells.

There are several different forms of sickle cell disease:

• Hemoglobin SS, also called sickle cell anemia, is usually the most severe type of this disorder.

Other common forms include:

• Hemoglobin SC (usually mild)
• Hemoglobin Sβ thalassemia

Rare types are:

• Hemoglobin SD
• Hemoglobin SE