The blood smear of a patient shows the following on examination.The most probable condition involved is?
A. G6PD deficiency.
B. Liver diseases.
C. Lead poisoning.
D. All of the above.
Basophilic Stippling is seen in the image.
Ans: C. Lead Poisoning
- Basophilic Stippling is the term used to indicate the presence of irregular basophilic granules in the cytoplasm of erythrocytes. The granules are composed of unstable RNA and may be fine of coarse.
Basophilic stippling can be seen in a variety of hematologic disorders like:
- Thalassemias; heavy metal poisoning, particularly lead or arsenicals; dyserythropoietic anemias; megaloblastic anemia,thrombotic thrombocytopenic purpura and pyrimidine 5′-nucleotidase deficiency.