Which among the following is the most probable diagnosis for the karyotype shown below?
A. Down’s syndrome.
B. Klinefelter’s syndrome.
C. Turner syndrome.
D. None of the above.
Ans: B. Klinefelter’s syndrome.
The karyotype shown above represents Klinefelter’s syndrome because of trisomy at sex chromosome – XXY as represented by a red box in the picture below.
Klinefelter syndrome also known as 47,XXY or XXY, is the set of symptoms that result from two or more X chromosomes in males.
- They have 47 number of chromosomes instead of 46.
- Occurs in 1:500 to 1:1000 live male birth
- The primary feature is sterility