Question
A female patient is presenting with thin, purulent, and mildly odorous vaginal discharge,painful urination and mild pain in the abdomen.
Microscopic picture of the vaginal discharge is shown in the image.Which is the most common immune deficiency for the causation of this infection?
A. IgE deficiency
B. HLA b27.
C. Complement deficiency .
D. IgA deficiency.
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Correct Answer » C Explanation |
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Ans:C. Complement deficiency
The micro-organism shown in the photomicrograph above represents Neisseria gonorrhoeae.The female patient is suffering from Gonorrhea.
- Morphology of Neisseria gonorrhoeae: Gram-negative cocci that typically appear in pairs with the opposing sides flattened (a “kidney bean” appearance).
- The complement system is an essential component of the innate immune defence against infection by Neisseria (N. Meningitidis and N. gonorrhoeae).
- People who lack or have a deficiency in complement mediated bactericidal activity are most susceptible to neisserial diseases.
- Vaccinations for encapsulated organisms is crucial for preventing infections in complement deficiencies