Question
Which among the following is the most sensitive test for the micro-organism shown in the photomicrograph below?
A. VDRL.
B. RPR.
C. FTA-ABS.
D. Kahn.
Show Answer
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Correct Answer » C
Explanation
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Ans: C. FTA-ABS.
The micro-organism shown in the photomicrograph above represents Treponema.
Types of tests for Syphilis
Non-Treponemal Tests:
- Venereal Disease Research Laboratory (VDRL) test
- Rapid plasma reagin (RPR)
Treponemal Tests:
- Fluorescent treponemal antibody absorption test (FTA-ABS)
- T pallidum particle agglutination (TP-PA)
- Enzyme immunoassay (EIA)
Sensitivity of Syphilis Tests
|
Primary Syphillis |
Secondary Syphilis |
Latent Syphilis |
Tertiary Syphilis |
| RPR/VDRL |
78%-86% |
100% |
95%-100% |
71%-73% |
| FTA-ABS |
84% |
100% |
100% |
96% |
| TP-PA |
89% |
100% |
100% |
Data not yet available |
| EIA |
82%-100% |
100% |
98-100% |
Data not yet available |
- All the serological tests have 100% sensitivity in secondary stage of syphilis.
- Amongst the given options FTA – ABS is most sensitive.
