Question
A 25 year old male suffering from productive cough,fever ,night sweats and weight loss since 2 months.He undergone a skin test as shown in the image..This test is based on which hypersensitivity reaction?
A. Type 1.
B. Type 2.
C. Type 3.
D. Type 4.
Show Answer
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Correct Answer » D
Explanation
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Ans:D. Type 4
The test shown in the photograph above represents Mantoux test.
Hypersensitivity reaction
- Hypersensitivity is a set of undesirable reactions produced by the normal immune system, including allergies and autoimmunity.
Comparison of hypersensitivity types
| Type |
Alternative names |
Often mentioned disorders |
Mediators |
| I |
Allergy (immediate) |
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| II |
Cytotoxic, antibody-dependent |
- Autoimmune hemolytic anemia
- Rheumatic heart disease
- Thrombocytopenia
- Erythroblastosis fetalis
- Goodpasture’s syndrome
- Graves’ disease
- Myasthenia gravis
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- IgM or IgG
- (Complement)
- MAC
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| III |
Immune complex disease |
- Serum sickness
- Arthus reaction
- Rheumatoid arthritis
- Post streptococcal glomerulonephritis
- Membranous nephropathy
- Lupus nephritis
- Systemic lupus erythematosus
- Extrinsic allergic alveolitis (hypersensitivity pneumonitis)
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- IgG
- (Complement)
- Neutrophils
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| IV |
Delayed-type hypersensitivity, cell-mediated immune memory response, antibody-independent |
- Contact dermatitis.
- Mantoux test
- Chronic transplant rejection
- Multiple sclerosis
- Celiac Disease
- Hashimoto’s thyroiditis – Some type 2. Mostly type 4.
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| V |
Autoimmune disease, receptor mediated |
- Graves’ disease
- Myasthenia gravis
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