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Image Based Question-65762

Neelam Maurya

A female mouse gathers, grooms and nurses her 3-day-old pups in the research lab of assistant professor of zoology Stephen Gammie. Gammie has studied the link between maternal aggression in mice and levels of a peptide hormone that controls behavior, particularly an animal's response to fear and anxiety. ©UW-Madison University Communications 608/262-0067 Photo by: Michael Forster Rothbart Date: 7/04 File#: D100 digital camera frame 5909

Question

Animals (Encircled) shown in image are used for isolation of which virus which are transmitted by the fecal-oral route ?

A. Poxvirus

B. Adenovirus

C. Herpes virus

D. Coxsachie virus

 

Show Answer

Correct Answer » D

Explanation

Ans:D. Coxsackie virus

Animal is suckling mice

Coxsackievirus

  • It is a virus that belongs to a family of nonenveloped, linear, positive-sense single-stranded RNA viruses, Picornaviridae and the genus Enterovirus, which also includes poliovirus and echovirus. Enteroviruses are transmitted by the fecal-oral route.
  • The coxsackieviruses were subdivided into groups A and B based on their pathology in newborn mice.
  • Both group A and group B coxsackieviruses can cause nonspecific febrile illnesses, rashes, upper respiratory tract disease, and aseptic meningitis.
  • Group A coxsackieviruses tend to infect the skin and mucous membranes, causing herpangina, acute hemorrhagic conjunctivitis, and hand, foot, and mouth (HFM) disease.
  • Group B coxsackieviruses tend to infect the heart, pleura, pancreas, and liver, causing pleurodynia, myocarditis, pericarditis, and hepatitis
  • It is necessary to employ suckling mice for the isolation of coxsackie viruses.
  • Inoculation is usually made by intracerebral, subcutaneous and intraperitoneal route.
  • Adult mice are not susceptible.
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