Question
The disorder shown in the picture below is detected by which urine test?
A. Guthrie test.
B. Sodium nitroprusside test.
C. Blot test.
D. FeCl3.
Show Answer
Correct Answer » A
Explanation
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The disorder shown in the picture above represents Phenylketonuria as the child is showing the features of microcephaly, blonde hair.
Guthrie Test:
It is a rapid screening test.
Certain strains of bacillus subtilis need phenylalanine as an essential growth factor.
Bacteria cannot grow in a medium devoid of phenylalanine.
Bacterial growth is proportional to the phenylalanine content in the patient’s blood.
Good to know:
- Ferric chloride Test: Phenyl ketones in urine can be detected by this test. A transient blue-green color is a positive test.
- Nitroprusside Test is used for the colour reaction of amino acid Sulfhydryl group (Cysteine.)
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