Image Based Question – 66412

Identify the childhood malignancy shown in the photograph below by looking at the eyes ?

A. Retinoblastoma.

B. Neuroblastoma.

C. Meningioma.

D. Wilm’s tumour.

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Correct Answer » B Explanation

Neuroblastoma is the most common extracranial solid tumor of infancy.

• It is an embryonal malignancy of the sympathetic nervous system arising from neuroblasts (pluripotent sympathetic cells).

• In the developing embryo, these cells invaginate, migrate along the neuraxis, and populate the sympathetic ganglia, adrenal medulla, and other sites.

• The patterns of distribution of these cells correlates with the sites of primary neuroblastoma presentation.