A. Occurs only with a closed growth plate.
B. Abuts articular surface: 84-99% come within 1 cm of the articular surface.
C. Well defined with non-sclerotic margin (though < 5% may show some sclerosis).
D. All of the above.
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Correct Answer » D
Explanation
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Giant cell tumours (GCTs) of bone, also known as osteoclastomas, are relatively common bone tumours, usually benign which are arising from metaphysis and typically extending into the epiphysis of the long bones.
Radiographic features
Classic appearance
There are four characteristic radiographic features when a GCT is located in a long bone:
- occurs only with a closed growth plate.
- abuts articular surface: 84-99% come within 1 cm of the articular surface.
- well defined with non-sclerotic margin (though < 5% may show some sclerosis )
- eccentric: if large this may be difficult to assess
- Plain film and CT
General radiographic features include:
- narrow zone of transition: a broader zone of transition is seen in more aggressive GCTs
- no surrounding sclerosis: 80-85%
- overlying cortex is thinned, expanded or deficient
- periosteal reaction is only seen in 10-30% of cases
- soft tissue mass is not infrequent
- pathological fracture may be present
- no matrix calcification/mineralisation.
