A. 1,2,3 true & 4,5 false.
B. 2,5 true & 1,3,4 false.
C. 2,3,4 true & 1,5 false.
D. All are true.
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Correct Answer » B
Explanation
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The orthopaedic disorder shown in the picture above represents paget’s disease.
The tibia is the bone affected most commonly.
It is also seen in other bones like ilium, femur, skull, vertebrae, humerus, pelvis, spine and skull.
It is rarely diagnosed in people < 40 years of age.
Men are more commonly affected than females.
An elevated level of alkaline phosphatase in elderly patients are suggestive of paget’s disease.
Serum calcium and phosphate levels are normal in paget’s disease.
A variety of tumor and tumor like conditions develops in paget’s disease.
The benign lesions include: giant cell tumor, giant cell reparative granuloma and extraosseous mass of hematopoiesis.
The most dreaded is the conversion to sarcoma, which occurs in 0.7% to 0.9% of cases.
The sarcomas are usually osteosarcoma, malignant fibrous histiocytoma, orchondrosarcoma, and they arise in long bones, pelvis, skull and spine.
