Question
Condition shown in Photograph is characterized by all EXCEPT
A. Autosomal dominant
B. More than 50 Colonic adenomas diagnostic
C. Surgery is almost always advisable
D. Associated with desmoids tumors and osteomas
Show Answer
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Correct Answer » B
Explanation
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More thin 50 Colonic adenomas diagnostic (Familial Adenomatous Polyposis: More than 100 are diagnostic)
Familial adenomatous polyposis (FAP) is an inherited condition in which numerous adenomatous polyps form mainly in the epithelium of the large intestine. While these polyps start out benign, malignant transformation into colon cancer occurs when they are left untreated.
If malignancy develops, this may present with weight loss, altered bowel habit, or even metastasis to the liver or elsewhere. FAP can also develop ‘silently’ in some individuals, giving few or no signs until it has developed into advanced colorectal cancer.