A. Less prevalent in developing countries.
B. Toxicogenic strains usually causes ulcers.
C. Urea breath test is positive.
D. Gram negative organism.
Organism shown in the picture above represents Helicobacter pylori.
H. pylori infection are inane prevalent in developing countries.
The prevalence of H. pylori is approx. 30% in U.S. and other developed countries as against > 80% in most developing countries.
H. Pylori is a gram negative, spiral, flagellated bacillus – Harrison
Strains producing toxins (strains possessing cag pathogenicity DNA island) are more likely to give rise to severe gastritis, peptic ulceration and gastric cancer than strains without it.
DNA island or cag pathogenicity island is a large region of DNA which has genes that control production of toxins.
Urea breath test is a simple, inexpensive and consistently accurate test for H.pylori detection