Image Based Question-68005

Investigation for choice for the GIT infection by the micro-organism shown in the image is:

A. Histological examination from two sites after endoscopic biopsy, combined with either a rapid urease test or microbial culture

B. Blood antibody test

C. Stool antigen test

D. Urine ELISA test .

Show Answer

Correct Answer » A Explanation

Answer :A.  Histological examination from two sites after endoscopic biopsy, combined with either a rapid urease test or microbial culture.

H. pylori organism is shown in the image

Diagnosis of H.Pylori:

Testing for H. pylori is recommended if peptic ulcer disease or low-grade gastric MALT lymphoma is present, after endoscopic resection of early gastric cancer, first-degree relatives with gastric cancer, and in certain cases of dyspepsia,not routinely.

• Blood antibody test

• Stool antigen test

• Carbon urea breath test (in which the patient drinks 14C—or 13C-labelled urea, which the bacterium metabolizes, producing labelled carbon dioxide that can be detected in the breath).

• Urine ELISA test .

• The most accurate method for detecting H. pylori infection is with a histological examination from two sites after endoscopic biopsy, combined with either a rapid urease test or microbial culture.

• H. pylori can be demonstrated in tissue by Gram stain, Giemsa stain, haematoxylin–eosin stain, Warthin–Starry silver stain, acridine orange stain, and phase-contrast microscopy.