Hemolytic anemia is associated with …”””type of stones (PhotograPh)
D. None of the above
Ans :A. Pigmented type
Clinical manifestations may include the following:
- In intravascular hemolysis, iron deficiency due to chronic hemoglobinuria can exacerbate anemia and weakness.
- Tachycardia, dyspnea, angina, and weakness occur in patients with severe anemia, as cardiac function is sensitive to anoxia.
- Persistent hemolysis may result in the development of bilirubin(pigmented) gallstones; these patients may present with abdominal pain.
- Bronze skin color and diabetes occur in hematosiderosis; iron overload may occur in patients who have received multiple transfusions or those who have been administered iron therapy erroneously.
- Dark urine may be due to hemoglobinuria
- In addition to hemolysis, patients with thrombotic thrombocytopenic purpura (TTP) may experience fever, neurologic signs, renal failure, and thrombocytopenia.
- Leg ulcers may develop in patients with sickle cell anemia and other hemolytic disorders, as a result of decreased red blood cell (RBC) deformability and endothelial changes.