Question
Identify the probable condition by looking at the images.
A. Adrenal insufficiency
B. Pseudo-hypoparathyroidism
C. Cretinism
D. Diabetes Mellitus type:1
Show Answer
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Correct Answer » B
Explanation
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Ans:B. Pseudo-hypoparathyroidism
Pseudohypoparathroidism
- Albright’s hereditary osteodystrophy(Pseudohypoparathyroidism) is a disorder is characterized by a lack of responsiveness to parathyroid hormone, resulting in low serum calcium, high serum phosphate, and appropriately high serum parathyroid hormone.
- Individuals with Albright’s hereditary osteodystrophy have short stature, characteristically shortened fourth and fifth metacarpals, rounded facies, and often mild mental retardation.
- Albright’s hereditary osteodystrophy is commonly known as Pseudohypoparathyroidism because the kidney responds as if parathyroid hormone were absent. In fact, blood levels of parathyroid hormone are elevated in Pseudohypoparathyroidism due to the continued Hyperphosphatemia & Hypocalcemia.
- The absence of the fourth knuckle on each hand is characteristic of Albright’s hereditary osteodystrophy.
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