Image Based Question – 68244

Condition shown in the Photograph is a late complication of

A. Lung cancer

B. Pancreatic cancer

C. Grave’s disease

D. Addison’s disease

Show Answer

Correct Answer » C Explanation

Ans:C. Graves disease

Condition shown in the image is Pretibial Myxoedema

Pretibial myxedema /thyroid dermopathy

• It is a term used to describe localized lesions of the skin resulting from the deposition of hyaluronic acid, usually as a component of thyroid disease.

• Although it is most often confined to the pretibial area, it may occur anywhere on the skin, especially the ankle, dorsum of the foot, knees, shoulders, elbows, upper back, pinnae, nose, and neck.

• It is nearly always associated with autoimmune thyroid disease (ie, Graves Disease).Pretibial myxedema occurs in 0.5-4.3% of patients with Graves disease.

• It has also been reported, but much less frequently, in patients with Hashimoto thyroiditis, primary hypothyroidism, and euthyroidism.

• Peak incidence occurs in the fifth to sixth decades of life.

• Women are affected more frequently than men, with a female-to-male ratio of 3.5:1.